A SINGLE INSTITUTION RETROSPECTIVE REVIEW OF RADICAL RADIOTHERAPY OUTCOMES FOR CANCER OF THE OESOPHAGUS REPORTS ZERO TOXICITY.

A SINGLE INSTITUTION RETROSPECTIVE REVIEW OF RADICAL RADIOTHERAPY OUTCOMES FOR CANCER OF THE OESOPHAGUS REPORTS ZERO TOXICITY.

A single institution retrospective review of radical radiotherapy outcomes for cancer of the
oesophagus reports zero toxicity.
Discuss the implications of this statement from a RADIOBIOLOGICAL VIEWPOINT, with
particular reference to tumour control.
2. How do early and late radiation reactions differ with respect to latency, rates of evolution
once established, fractionation sensitivity and the effects of overall treatment time?
List and define reaction scoring systems in common clinical use and give one example of
how they rank an early and a late reaction.
How are dose-response data for these endpoints plotted on graphs?
3. Discuss the RADIOBIOLOGICAL RATIONALE for pre-, post- and intra-operative radiation
therapy.
4. How would you describe the underlying principles of CHART to an interested medical
colleague?
Can you suggest how the CHART schedule might be modified to make it more generally
applicable?
5. Write short notes on three of the following:
a. Stochastic effects of ionising radiation
b. Tumour suppressor genes
c. Western blotting
d. The CDK-cyclin complex


 

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