Competitive inhibitor which will inhibit the methylation of Protein phosphate 2A

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Competitive inhibitor which will inhibit the methylation of Protein phosphate 2A (PP2A) Via LCMT-1
Essay, Biology
The aim of the project is to find a Competitive inhibitor which will inhibit the methylation of Protein phosphate 2A (PP2A) Via LCMT-1.
Project Description
LCMT-1 – biochem side, role, function, why its function is important, why affecting its activity is important
phosphorylation
PP2A – biochem side, role, function, why its function is important, affecting its activity is important
PP2A & LCMT-1 Complexes
CAD – Molecular modeling techniques – molecular docking, why they are important, how they can help, how they work
Protein data bank
The aim of the project is to find Competitive inhibitors from a range of 75 potential ligands from a fragment library which will inhibit the methylation of Protein phosphate 2A (PP2A) Via LCMT-1. This is in the process of being achieved.
This investigation is about finding a competitive inhibitor that will stop the methylation of PP2A

 

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