which causes the drug to be less effective. How many 10-mg tablets are required for 30 days of treatment?

To prevent attacks of angina, isosorbide dinitrate is given typically at doses of 120 mg/day, divided into three separate doses.
For one week’s regimen, how many 10-mg sublingual tablets of isosorbide dinitrate will be needed?

 

To prevent attacks of angina, isosorbide mononitrate is given twice daily typically at doses of 20 mg. It is administered at specific times, such as 8 AM and 3 PM, to prevent nitrate tolerance, which causes the drug to be less effective. How many 10-mg tablets are required for 30 days of treatment?

Nitroglycerin is administered by IV infusion in emergency situations. A typical infusion dose is 5 micrograms per minute. For a diluted nitroglycerin solution with a concentration of 100 micrograms per milliliter, what is the infusion rate in milliliters per hour?

For acute angina attacks, sublingual nitroglycerin is often used. By placing a tablet under the tongue, relief can be obtained within 5 minutes. As many as three doses can be administered in a 15-minute period, after which medical attention is recommended. The dose of nitroglycerin per tablet is 0.6 mg. What is the total dose of nitroglycerin that can be safely administered in 15 minutes?


 

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